Muscle Relaxers: What They Are, Uses, Side Effects & Types

Muscle Relaxers: What They Are, Uses, Side Effects & Types

Yes, you can take cyclobenzaprine and Tylenol (acetaminophen) together. There are no known interactions between these medicines, however this doesn’t necessarily mean that no interaction exist. Prescription muscle relaxers are stronger than OTC options but may come with more pronounced side effects. We’ll also discuss what muscle relaxers are, how they work, and their side effects and precautions.

Valerian can be used as an effective herbal muscle relaxer, but not in combination with other pills. There is no known drug interaction between Tylenol (acetaminophen) and Vyvanse (lisdexamfetamine). However, if your doctor prescribes Vyvanse for ADHD, it is a good idea to talk with them about any potential Vyvanse interactions.

So, it’s not unheard of for an orthopedic doctor to co-prescribe both drugs in an attempt to give the patient short-term pain relief. Healthcare providers mainly prescribe antispastic muscle relaxers to treat spasticity. MRitonavir-boosted nirmatrelvir interacts with certain conjugated mAbs, such as ado-trastuzumab emtansine, mirvetuximab soravtansine, brentuximab vedotin, enfortumab vedotin, polatuzumab vedotin, and tisotumab vedotin.

Be sure to talk to your healthcare provider about all the options available to treat your symptoms. Indeed, muscle relaxers are effective drugs that can be used to manage acute and chronic pain. Since they can also be bought over-the-counter, users of these medications should know that some drugs and substances can interact with them. Whether an individual is suffering from lower back pain or spasticity, it is essential to get them treated.


Gabapentin is an anticonvulsant medication that works by decreasing abnormal excitement in the brain. Many patients use this drug to control seizures and relieve nerve pain. When combined with muscle relaxers, this can lead to an increase in the severity of CNS side effects. Novocaine is a medication that belongs to the drug class local anesthetics.

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Therefore, they should be used at the lowest effective dose for the shortest duration. Understanding and treating the underlying cause of hallucinations or agitation is preferred. These behaviors can be due to infection, pain, medications that cause hallucinations or worsen mood and memory, environmental factors or social factors. While medications can be very helpful, some medications can cause new problems and should be avoided. Others might need their doses to be adjusted to provide benefits or to reduce side effects.

Most muscle relaxers act as central nervous system depressants and cause a sedative effect, or prevent your nerves from sending pain signals to your brain. It is also possible for serious cyclobenzaprine side effects to occur, like seizures, heart arrhythmias, heart attack, or stroke. These are more likely to occur when a person has too much cyclobenzaprine in their system, for instance, if their prescription dose is too high or if they are misusing the drug. Patients who are receiving higher doses of dexamethasone will be at a greater risk of AEs.


If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Because of the possibility of higher blood levels in the elderly as compared to younger adults, use of cyclobenzaprine extended-release capsules is not recommended in the elderly.

  • The drug interactions with Cymbalta and these drugs may also lead to serotonin syndrome.
  • If someone has combined muscle relaxers for TMJ with other drugs, it is better to seek help.
  • In case of muscle relaxers addiction, getting help from rehab centers would be a great choice.
  • Cymbalta belongs to the drug class called selective norepinephrine reuptake inhibitors (SNRIs).

Ritonavir-boosted nirmatrelvir is contraindicated in this setting because the delayed offset of enzyme induction may reduce the concentrations of nirmatrelvir and ritonavir, rendering the treatment ineffective against SARS-CoV-2. During pregnancy, this medication should be used only when clearly does flexeril make you sleepy the next day needed. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Before taking cyclobenzaprine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.

Aleve or Naproxen is a non-steroidal anti-inflammatory drug and patients use it to manage pain caused by headaches, muscle aches, tendonitis, dental pain, and menstrual cramps. Although useful for patients with pain conditions, it is important to understand that one can go for this combination as Aleve does not have any muscle relaxers interactions. According to a study published in the US National Library of Medicine National Institutes of Health, the combination therapy consisting of naproxen and muscle relaxant benefits patients with acute low strain than this drug alone. Supplements like St. John’s Wort used for depression can have serious drug interactions with Vyvanse leading to serotonin syndrome. If your doctor prescribes Vyvanse, be sure to tell them about all the dietary supplements, herbal remedies, and over-the-counter medications you are taking.

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